One-pot synthesis of benzo[1,4]thiazin-3(4H)-ones and a theoretical study of the S–N type Smiles rearrangement mechanism

Benzo[1,4]thiazin-3(4H)-one derivatives are conveniently prepared in one pot via a Smiles rearrangement (SR) tandem reaction. In order to understand the reaction, we present here a theoretical study on the S–N type SR mechanism.