Prevalence of clonal hematopoiesis of indeterminate potential (CHIP) measured by an ultra-sensitive sequencing assay: Exploratory analysis of the Circulating Cancer Genome Atlas (CCGA) study.

Charles Swanton,Oliver Venn,Alex Aravanis,Earl Hubbell,Tara Maddala,John F. Beausang,Darya Filippova,Samuel Gross,Arash Jamshidi,Ling Shen,Anton Valouev,Nan Zhang,Kelly L Bolton,Timothy J. Yeatman,Michael V. Seiden,Geoffrey R. Oxnard,Minetta C. Liu,Richard Williams,Anne-Renee Hartman,José Baselga

Prevalence of clonal hematopoiesis of indeterminate potential (CHIP) measured by an ultra-sensitive sequencing assay: Exploratory analysis of the Circulating Cancer Genome Atlas (CCGA) study.

2018

12003Background: CHIP is defined by the presence of age-dependent acquired mutations in hematopoietic progenitor cells and has been reported to occur in up to 30% of individuals 60-70 years of age....

Keywords:

Cancer
Haematopoiesis
Genome
Pathology
Cancer research
Medicine
exploratory analysis
ultra sensitive
cancer genome
Indeterminate
Hematopoietic progenitor cells
clonal hematopoiesis

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