Variant Manifestation of Cowden Disease in Japan: Hamartomatous Polyposis of the Digestive Tract with Mutation of the PTEN Gene

The authors thank the patient and members of his family, for their participation in this study, and Prof. Tetsuro Miki for advice and encouragement. This work was supported by a Grant-in-Aid for priority areas “Cancer Research” and “Genome Science” from the Ministry of Education, Science, Sports and Culture of Japan and by a Research Grant for Cancer Research from the Ministry of Health and Welfare of Japan.