A limited sampling model to estimate exposure to lenalidomide in multiple myeloma patients.

Seiji Shida,Naoto Takahashi,Masatomo Miura,Takenori Niioka,Morio Matsumoto,Masao Hagihara,Takahiro Kobayashi,Maiko Abumiya,Yoshihiro Kameoka,Naohito Fujishima,Hiroyuki Tagawa,Makoto Hirokawa,Kenichi Sawada

A limited sampling model to estimate exposure to lenalidomide in multiple myeloma patients.

2014

Seiji Shida
Naoto Takahashi
Masatomo Miura
Takenori Niioka
Morio Matsumoto
Masao Hagihara
Takahiro Kobayashi
Maiko Abumiya
Yoshihiro Kameoka
Naohito Fujishima
Hiroyuki Tagawa
Makoto Hirokawa
Kenichi Sawada

Background:The aim of this study was to develop a model able to predict the area under the lenalidomide plasma concentration–time curve (AUC) in multiple myeloma (MM) patients using a limited sampling strategy.Methods:Forty-six hospitalized Japanese MM patients (25 men and 21 women) participated in

Keywords:

Anesthesia
Lenalidomide
Cancer research
Sampling (statistics)
Medicine
Multiple myeloma
Oncology
limited sampling
Internal medicine

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