Advances in research on malaria transmission blocking vaccines.

This paper summarizes the common candidate antigens in transmission blocking vaccines (TBVs) and discusses the status quo of research on antigen vaccines before and after fertilization of gametes, as well as the relevant antigen vaccines in the body of mosquitoes. The hotspots in TBVs such as the study of reactionogenicity of candidate antigens and practical effects of adjuvants and their prospects are also reviewed to provide the basis for further research on malaria transmission blocking vaccines.