Characterization of concurrent target suppression by JNJ-61178104, a bispecific antibody against human tumor necrosis factor and interleukin-17A.

Songmao Zheng,Fang Shen,Brian Jones,Damien Fink,Brian Geist,Ivo P. Nnane,Zhao Zhou,Jeff Hall,Ravi Malaviya,Tatiana Ort,Weirong Wang

Characterization of concurrent target suppression by JNJ-61178104, a bispecific antibody against human tumor necrosis factor and interleukin-17A.

2020

Songmao Zheng
Fang Shen
Brian Jones
Damien Fink
Brian Geist
Ivo P. Nnane
Zhao Zhou
Jeff Hall
Ravi Malaviya
Tatiana Ort
Weirong Wang

Tumor necrosis factor (TNF) and interleukin (IL)-17A are pleiotropic cytokines implicated in the pathogenesis of several autoimmune diseases including rheumatoid arthritis (RA) and psoriatic arthri...

Keywords:

Interleukin
bispecific antibody
Pathogenesis
Necrosis
Immunology
Rheumatoid arthritis
Interleukin 17
Biology
Tumor necrosis factor alpha
human tumor

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