A rare case of acquired amegakaryocytic thrombocytopenic purpura and its clinical care

Introduction : Acquired amegakaryocytic thrombocytopenia is an unusual and rare hematologic disorder characterized by thrombocytopenia along with markedly reduced bone marrow megakaryocytes. Patients usually present with thrombocytopenia and severe bleeding that is unresponsive to steroids and intravenous immunoglobulin. Case : In our study, a 52-year-old female was diagnosed with acquired amegakaryocytic thrombo cytopenia and was treated with a combination of immunosuppressants namely antithymocyte globulin, methylprednisolone and cyclosporine. OUTCOME: Symptoms improved significantly following treatment and we confirm the successful management of this rare disease entity with combined immuno suppression therapy