A Randomized Phase III Study Comparing Weekly Folinic Acid(FA) and High-Dose 5-Fluorouracil (5-FU) with Monthly 5-FU/FA (days 1-5) in Untreated Patients with Metastatic Colorectal Carcinoma

H. J. Weh,R. Zschaber,D. Braumann,P. Hoelzer,R. Hoffmann,Karl-Friedrich Becker,U. R. Kleeberg,R. Pompecki,M. Hoffknecht,A. Benner,D.K. Hossfeld

A Randomized Phase III Study Comparing Weekly Folinic Acid(FA) and High-Dose 5-Fluorouracil (5-FU) with Monthly 5-FU/FA (days 1-5) in Untreated Patients with Metastatic Colorectal Carcinoma

1998

H. J. Weh
R. Zschaber
D. Braumann
P. Hoelzer
R. Hoffmann
Karl-Friedrich Becker
U. R. Kleeberg
R. Pompecki
M. Hoffknecht
A. Benner
D.K. Hossfeld

Background: The combination of 5-fluorouracil (5-FU) and folinic acid (FA) given over 5 days every 4 weeks is one of the most frequently used regimens in metastatic colorectal carci

Keywords:

Phases of clinical research
Fluorouracil
Confidence interval
Colorectal cancer
Folinic acid
Gastroenterology
Pathology
Progressive disease
Surgery
Statistical significance
Internal medicine
Medicine
Diabetes mellitus

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