Anti-filarial IgG antibodies in patients with bancroftian filariasis and tropical pulmonary eosinophilia.
1985
Anti-filarial (anti- B. malayi adult as well as anti- B. malayi microfilarial) IgG antibody levels were measured by enzyme
linked immunosorbent assay (ELISA) in asymptomatic microfilaria carriers, acute, chronic and tropical pulmonary
eosinophilia (TPE) patients, endemic and non-endemic controls. Controls from endemic areas had higher antibody titres
compared with controls from non-endemic areas. The antibody response in different groups of filariasis patients was not stage
specific. There were no association between clinical disease and antibody levels except in TPE. Though TPE patients had very
high antibody levels, a proportion of them had low levels suggesting heterogeneity in TPE population.
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