trans-1,2-Diaminocyclohexane Mesoporous Silica for Asymmetric Catalysis: Enhancement of Chirality Through Confinement Space by the Plug Effect.

Highly enantioselective addition of α,β-unsaturated ketones to nitroalkenes is achieved at ambient temperature in the presence of a protonic acid and trans-1,2-diaminocyclohexane functionalized mesoporous silica as catalyst.