Synthesis of (±)-5′-methoxyhydnocarpin-D, an inhibitor of the Staphylococcus aureus multidrug resistance pump

Abstract The total synthesis of regioisomerically pure (±)-5′-methoxyhydnocarpin-D ( 6 ) from commercially available vanillin ( 7 ), methyl gallate ( 9 ) and 2′,4′,6′-trihydroxyaceophenone ( 10 ) is achieved.