A phase I study of multi-HLA-binding HSP70 + GPC3 peptides and combination adjuvants of LAG3-Ig + Poly-ICLC against gastrointestinal cancers.

Shoichi Hazama,Koji Tamada,Keiko Udaka,Yasunari Koki,Toshinari Uematsu,Hideki Arima,Tomomitsu Satoh,Shun Doi,Tomoya Miyakawa,Hiroto Matsui,Shinsuke Kanekiyo,Yukio Tokumitsu,Kazuhiko Sakamoto,Nobuaki Suzuki,Shigeru Takeda,Shigeru Yamamoto,Shigefumi Yoshino,Tomio Ueno,Hiroaki Nagano

A phase I study of multi-HLA-binding HSP70 + GPC3 peptides and combination adjuvants of LAG3-Ig + Poly-ICLC against gastrointestinal cancers.

2018

Shoichi Hazama
Koji Tamada
Keiko Udaka
Yasunari Koki
Toshinari Uematsu
Hideki Arima
Tomomitsu Satoh
Shun Doi
Tomoya Miyakawa
Hiroto Matsui
Shinsuke Kanekiyo
Yukio Tokumitsu
Kazuhiko Sakamoto
Nobuaki Suzuki
Shigeru Takeda
Shigeru Yamamoto
Shigefumi Yoshino
Tomio Ueno
Hiroaki Nagano

e15167Background: Based on the exploratory analysis of our previous studies of peptide vaccine, we concluded that the combination of adjuvants hLAG-3Ig + Poly-ICLC is essential for controlling nega...

Keywords:

Poly ICLC
Cancer research
LAG3
Pathology
Human leukocyte antigen
Medicine
exploratory analysis
Immunology
Peptide vaccine
Hsp70
phase i study

Correction
Source
Cite
Save
Machine Reading By IdeaReader

References

Citations