Complicated Atazanavir-Associated Cholelithiasis: A Report of 14 Cases

Fourteen human immunodeficiency virus (HIV)―infected patients receiving an atazanavir (ATV)―based antiretroviral regimen developed complicated cholelithiasis. ATV was found in biliary calculi in 8 of 11 cases: infrared spectrome-try analysis of calculi revealed that ATV made up a median of 89% (range, 10%―100%) of the total calculus composition. Development and management of ATV-associated cholelithiasis are discussed.