Method of inhibiting the replication of viruses

A method of inhibiting the replication of hepatitis C virus having a 3'-end (3'-UTR) of the viral genome located untranslated region, characterized in that a the 3 'UTR sequence forming section using a short double-stranded ribonucleic acid (dsRNA) is cut, wherein the one strand of the dsRNA in sections or completely complementary to the 3 'UTR sequence is the viruses.