Standardization of Rat Blood Clotting Tests with Reagents Used for Humans

Adult male Wistar rats (200 to 300 g) from the colony of the School of Medicine (UNAM), Mexico City, were used. Animals were distributed among groups according to the balanced, Latin-square block design based on body weight. Room temperature was kept con-stant (20-22°C) with 12-12 h light-dark cycles and food and water