Математическое моделирование для дозиметрического планирования радиойодтерапии пациентов с заболеваниями щитовидной железы

This article deals with forming kinetic models of radioiodine distribution in the human thyroid. 5 patients with Grave's disease, 7 patients with nontoxic multinodular goiter and 2 patients with toxic adenoma received a pre therapeutic activity of 50-70 MBq. The thyroid uptake was measured 2-6 days after oral application with scintillation counter. The kinetic of radioiodine in the thyroid was calculate by use the three-chamber models. It was assumed that behaviour of 123I in the pre therapeutic situation would be same the 131I in the therapeutic setting. The measurements after the pre therapeutic administered activity of 123I were used to calculate the indicative administered dose from 131I.