Особенности кислотопродукции и патогенеза сочетанных осложнений у пациентов с пилорическими и препилорическими язвами желудка

Comparative analysis of acid production in 150 patients with duodenal ulcer disease and gastric ulcers of third type (H.D. Johnson's classification) was executed. In patients with duodenal ulcer disease specific individual rhythm of daily intragastric acidity was found. Found that the highest rise was observed at night. The features of gastric acid secretion were defined depending on the location of ulcerative substrate. Pathogenetic validity of antisecretory drugs in patients with duodenal ulcers was shown. The need for further improvements of the algorithm of treatment of patients with pyloric and prepyloric ulcers was demonstrated.