An Analysis Of Morbidity And Mortality Following Radical Cystectomy In e Treatment Of Invasive Bladder Cancer

Aim’s & Objectives: To analyse morbidity and mortality in patients with muscle invasive bladder cancer after radical cystectomy. Patients and Methods: A total  of 46 patients who underwent radical cystectomy between April  2010 to August 2015 at Nizam’s Institute Of Medical Sciences – Hyderabad were included in this retrospective study. Data regarding tumor stage before surgery was retrieved from data base. Tumor staged using the Tumors-Node-Metastasis classification system.Radical cystectomy was done for histologically proven muscle invasive cases on transurethral resection of bladder tumor. Mean followup period is 31 months.Patients were divided into node-positive and node negative groups and analysed to assess the survival. Results: Among 46 patients included in our study mean age is 60±5 years. 36.9% of patients presented with early complications like wound dehiscence(19.5%), pelvic collection (13%) and burst abdomen (4.3%) . During follow-up with mean follow up period of 31 months distant metastasis was noted in 8.6% of patients, 4.3% with pelvic recurrence and 2.1% with ureteric stricture. Survival in node-negative group was 80%  and in node-positive group was 52%. Conclusion: Radical cystectomy remains the main stay of treatment in muscle-invasive bladder cancer.Complications and survival are better with bladder confined disease compared to non organ confined disease. This is relatively safe procedure with minimal morbidity and mortality in selected patients.