Derivatives of piperidinyl, and piperazinyl-alkyl carbamates, their preparation and their therapeutic application

A compound having the general formula (I): wherein A represents a nitrogen atom or a CR2 group in which R2 represents a hydrogen, fluorine or hydroxyl, cyano, trifluoromethyl, C1-5 alkyl, C1-5-alkoxy; n represents an integer equal to 2 or 3 and m represents an integer equal to 2 when A represents a nitrogen atom; n represents an integer 1, 2 or 3 and m is an integer equal to 1 or 2 when A represents a group CR2; B represents a covalent bond or a C1-8 -alkylene group; R1 represents a group of aryl or heteroaryl type possibly substituted with one or more substituents selected from halogen, cyano, nitro, C1-5-alkyl, C1-3-alkoxy, C1-5-thioalkyl, C1- 5-fluoroalkyl, C1-3-fluoroalkoxy, C1-3-fluorothioalkyl, C3-5-cycloalkyl, C3-5-cycloalkyl-C1-3-alkylene, piperidinyl, pyrrolidinyl, morpholinyl, NH2, NHR6, NR6R7, NHCOR6, COR6, CO2R6, SO2R6, -O- (C1-3 -alkylene) -O-, phenyl, pyridinyl or pyrimidinyl; R3 represents a group of general formula CHR4CONHR5 wherein R4 represents a hydrogen atom or a C1-3-alkyl group and R5 represents a hydrogen atom or a C1-3-alkyl, C3-5-cycloalkyl, C3- 5-cycloalkyl-C1-3-alkylene; R6 and R7 independently of one another a C1-3-alkyl group; the base, of an addition salt with an acid, hydrate or solvate. therapeutic application.