Comparison between prochymosin and pepsinogen from lamb and calf

Abstract 1. 1. Prochymosin (EC 3.4.23.4) and pepsinogen A (EC 3.4.23.1) from Mongolian lamb ( Ovis platyurea ) were purified to homogeneity by salt precipitation, gel filtration and ion-exchange chromatography. 2. 2. Immunoelectrophoresis shows partial immunochemical identity between chymosins and pepsins from lamb and cattle, respectively. 3. 3. Activity determinations, N -terminal amino acid sequences and amino acid compositions also show a close relationship between the proteinases from lamb and cattle. 4. 4. Lamb prochymosin and pepsinogen are both glycosylated.