Reaction of aziridinium ions with organometallic reagents: optimization of the key step of ecopipam synthesis

David R. Andrews,Vilas H. Dahanukar,Jeffrey M. Eckert,Dinesh Gala,Brian S. Lucas,Doris P. Schumacher,Ilia A. Zavialov

Reaction of aziridinium ions with organometallic reagents: optimization of the key step of ecopipam synthesis

2002

David R. Andrews
Vilas H. Dahanukar
Jeffrey M. Eckert
Dinesh Gala
Brian S. Lucas
Doris P. Schumacher
Ilia A. Zavialov

Formation, stability and reactivity of aziridinium ions 3 towards organometallic reagents was explored and optimized for the efficient preparation of key drug intermediate 5c.

Keywords:

Electron affinity
Reagent
Ecopipam
Ion
Inorganic chemistry
Organic chemistry
Chemistry

Correction
Source
Cite
Save
Machine Reading By IdeaReader

References

Citations