Establishment of Model of Rats Infected by Ureaplasma Urealyticum

Objective This study observed the effects of Uu on the morphology of the testis of rats infected.Methods Rats were inoculated the Uu(105ccU/mL) by injecting broth into the urinary bladder following laparectomy.The testes of rats were used to detect Uu.Uu were obtained by PCR.The testes were observed with light microscope.Results 8 positive Uu rats were tested out in model group,the tested rate is 66.7%;no one was tested out in normal group,the weight of testis in model group is lower than that in normal group(P 0.01);The testis seminiferous tubules in normal group were normal,and germ cells’array was regular,and sperms could be often seen in the tubules.The changed seminiferous tubules,and the reduced germ cells in some area could be seen under light microscope in model group.Conclusion It has been shown that Uu interfere with spermatogenesis.Uu might be one of the causes of male infertility.