Diastereo- and Enantioselective Three-Component Coupling Approach to Highly Substituted Pyrrolidines.

Mani Raj Chaulagain,Albert E. Felten,Kevin E. Gilbert,Zachary D. Aron

Diastereo- and Enantioselective Three-Component Coupling Approach to Highly Substituted Pyrrolidines.

2014

Mani Raj Chaulagain
Albert E. Felten
Kevin E. Gilbert
Zachary D. Aron

The enantioselective synthesis of substituted pyrrolidines through a mild Lewis-acid catalyzed three-component coupling reaction between amino acids, heteroaromatic aldehydes, and olefins is reported.

Keywords:

Enantioselective synthesis
Coupling reaction
Catalysis
Coupling
Amino acid
Organic chemistry
Chemistry
pyrrole derivatives

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