RiZE YÖRESiNDEKi GEBE KADINLARDA SiTOMEGALOViRUS SEROPREVALANSI

Amac: Sitomegalovirus (CMV) Herpesviridae ailesinin Beta herpes virinae alt ailesinden bir DNA vi- rusudur. CMV enfeksiyonu yaygin bir enfeksiyondur ve gebelikte gecirilmesi gelismekte olan fetus icin ciddi zararlar meydana getirebilir. Bu calismada hastanemiz gebe poliklinigine basvuran gebe kadinlarda CMV'nin lgM ve lgG tipi antikorlarinin seroprevalanslarinin tespit edilmesi amaclanmis- tir. Literaturde, Rize yoresinde bu calismayla iliskili veri bulunmamaktadir Materyal ve Metod: Bu calismada hastanemiz gebe poliklinigine 2009-2014 tarihleri arasinda basvuran 874 gebenin CMV lgM ve 210 gebenin CMV lgG antikor degerleri retrospektif olarak incelendi. Bulgular: CMV lgG olcumune gore olgularin %0,5'inin (n=1) CMV lgG sonucu negatif, %99,5'inin (n=209) CMV lgG sonucu pozitif olarak saptanmistir. CMV lgM olcumune gore olgularin %96,9'unun (n=847) CMV lgM sonucu negatif, %0,5'inin (n=4) ara deger ve %2,6'sinin (n=23) CMV lgM sonucu pozitif olarak saptanmistir. Sonuc: Bu calisma ile Rize ilinde 5 yillik periyotta gebe poliklinigine basvuran gebe kadinlardaki CMV seroprevalansi belirlenmistir. Anahtar kelimeler: Sitomegalovirus; Seroprevalans; Gebelik ABSTRACT Aim: Cytomegalovirus (CMV) is a DNA virus of the Beta herpes virinae Subfamily And Herpes viridae Family. CMV infection is a common viral infection in pregnancy and may have severe consequences for the developing fetus. ln the present study we aimed to investigate seroprevalance of CMV lg M and lg G among pregnant women who were admitted to our obstetric outpatient clinic. To the best of our knowledge there has been no data in the literature of this subject in Rize region. Materials and Methods: ln this retrospective study, 874 pregnant women were investigated for CMV lgM antibodies and 210 pregnant women were investigated for CMV lgG antibodies, who were admitted to our obstetric outpatient clinic between 2009-2014 Results: CCMV lgG results of the patients were: 0,5% (n=1) negative, 99,5% (n=209) positive. CMV lgM results of the patients were: 96,9% (n=847) negative, 0,5% (n=4) gray zone and 2,6% (n=23) positive. Conclusion: ln the present study seroprevalance of CMV was detected among pregnant women who were admitted to our hospital for a 5-year period in Rize region Key words: Cytomegalovirus; Seroprevalence; Pregnancy