Variation in the α2A-adrenergic receptor gene and risk of gestational diabetes

Vivian K Kawai,Rebecca T. Levinson,Abiodun O. Adefurin,Daniel Kurnik,Sarah P Collier,Douglas Conway,Charles Michael Stein

Variation in the α2A-adrenergic receptor gene and risk of gestational diabetes

2017

Vivian K Kawai
Rebecca T. Levinson
Abiodun O. Adefurin
Daniel Kurnik
Sarah P Collier
Douglas Conway
Charles Michael Stein

Aim: Sympathetic activation suppresses insulin secretion via pancreatic ADRA2A. Because sympathetic activity and insulin demand increase during pregnancy, we tested the hypothesis that ADRA2A variants are associated with gestational diabetes (GDM).

Keywords:

Genetics
Endocrinology
Biology
Internal medicine
Gene
Adrenergic receptor
Diabetes mellitus
Gestational diabetes
Genetic variation
Insulin
Pregnancy
Pharmacology
Type 2 Diabetes Mellitus

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