A Case of Acute Monoblastic Leukemia with Hexasomy 8

Additional copies of chromosome 8 are nonrandom karyotypic aberrations in myeloid malignancies with trisomy 8 being the most common. Hexasomy 8 is extremely rare and only two cases have been reported. We report a case of acute myeloid leukemia with hexasomy 8 as a sole karyotypic aberration by conventional cytogenetic analysis. The patient was diagnosed as acute monoblastic leukemia and showed short survival. (Korean J Hematol 2002;37:223 226)