SPECIALISED TECHNIQUES FOR DEVELOPING ODT DOSAGE FORMS

technology for masking the bitter drug taste and rapidly dispersing microgranule technology. In this article, Dr Michelle Papp, Formulation Scientist, Dr Gopi Venkatesh, R&D Director, and Troy Harmon, Vice-President Business Development, all of Eurand, describe how, by removing lubricants from within the tablet formulation, an AdvaTab ODT provides important patient advantages through increased dissolution and disintegration rates. External lubrication also creates manufacturing advantages for partners, such as decreased overall production time and harder, more robust tablets that can be packaged in bottles or blisters. Eurand's recent commercialised AdvaTab products include Lamictal ® ODT with GlaxoSmithKline and Unisom ® SleepMelts with Chattem.