One patient with two different 18-fluorodeoxyglucose positron emission tomography/computed tomography views

A normoglycemic patient with a diagnosis of laryngeal cancer underwent F-18 Fluorodeoxyglucose Positron Emission Tomography/Computed Tomography (F-18 FDG PET/CT) for staging purposes and two different results were obtained. In the first assessment, F-18 FDG uptake of the primary lesion was very low, but a significant F-18 FDG uptake was noted in the second evaluation. F-18 FDG PET/CT is used for the diagnosis, staging and re-staging, as well as for the assessment of response to treatment in oncological patients. F-18 FDG uptake is associated with fasting blood glucose levels and satiety. The lower and upper limit of fasting blood glucose is variable between centers. In this present case report, we want to discuss the factors responsible for not detecting F-18 FDG uptake in the area of primary lesion in a normoglycemic patient with laryngeal cancer.