Increased dopamine after mating impairs olfaction and prevents odor interference with pregnancy.
2008
Pregnancy in mice is aborted if a female smells the urine of a new male up to 3 days after insemination, but not later. What changes? Dopamine increased in the female main olfactory bulb after copulation, peaking at 4 days. This diminished the mice's ability to recognize male urine. A dopamine receptor inhibitor improved recognition of male urine, and thereby increased the probability of abort.
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