Treatment of colonic bleeding in Klippel-Trenaunay syndrome with combined partial colectomy and endoscopic laser

Klippel-Trenaunay syndrome can be associated with significant lower gastrointestinal bleeding from diffuse cavernous hemangiomata of the colon. Distal colectomy is curative but the formation of a colostomy is undesirable in patients who already have a poor self-image due to the other manifestations of Klippel-Trenaunay syndrome such as multiple cutaneous hemangiomata, severe varicose veins, and prominent limb hypertrophy. Endoscopic laser ablation alone is often not feasible in these patients because of the extensive and often circumferential nature of the colonic hemangiomata. This report describes successful treatment of gastrointestinal hemorrhage due to colonic hemangiomata by a novel combination of partial colonic resection and endoscopic laser therapy.