Naso-Sinusal Tuberculosis: 3 Cases Report

Introduction: Tuberculosis remains a real public health problem in Tunisia. Extra-pulmonary localizations account for 20 to 30% of tuberculosis disease, dominated by the node, osseous and urogenital localization. Case Report: The authors present three cases of nasosinusal tuberculosis, an unusual and rare localization of the disease, in a man and 2 women aged respectively of 30, 65 and 36 years. Results: The main symptoms were dominated by nasal obstruction, posterior throwing and dental pain. CT-scan showed a filling of the nasosinusal cavities with various stages of bony lysis. In all the cases, tuberculosis was confirmed histologically after an endoscopic middle meatotomy. Investigations looking for tuberculosis elsewhere were negative in all cases. Treatment was based on anti-tuberculosis drugs during 9 to 12 months. The evolution was favourable in all the cases. Conclusions: Nasosinusal tuberculosis is a rare chronic infection associating often variable levels of bony lysis. Histological exam remains the best way to confirm it. Therapy is based on anti-tuberculosis drugs. Medical investigations must usually search other localizations of the disease.