Клинико-эпидемиологические особенности инфекции мочевыводящих путей у детей Приморского края

Summary: The review covers the findings of the epidemiological trial on urinary tract infections (UTI) incidence, acute and chronic pyelonephritis in children of Primorsky territory. The significant impact of environmental climatic and heliogeophysical risk factors on pyelonephritis morbidity in children was detected. The most significant factors of UTI development in Primorsky territory were defined. Clinical and laboratory features of this pathology in children at the present day are represented. The ideas of pathogenesis of bacterial inflammation in urinary tract have been broaden. The role of tumor necrosis factor-alpha and its type 2 soluble receptor in persistence and in progression of the inflammation process, which can lead to non-reversible sclerotic changes in kidney tissue, was determined. The role of nitrogen oxide in pathogenetic mechanisms of renal hypertension in children was determined. The complex rehabilitation of patients with local mineral water was considered. The obtained data can be used in further researches, in the work of children›s medical institutions of cities and regions of Primorsky territory.