Analysis outcomes and complications of twin pregnancy by in vitro fertilization-embryotransfer and intracytoplasmic sperm injection

Objective:To investigate the outcomes and complications of twin pregnancy by in vitro fertilization-embryotransfer(IVF-ET) and intracytoplasmic sperm injection(ICSI).Methods:A retrospective study was carried out to measure premature rupture of membrane,placental abruption,pregnancy-induced hypertension,intrahepatic cholestasis of pregnancy and abortion,437 twin pregnant women who achieved pregnancy by IVF—ET or ICSI in our hospital from February,2004 to May,2011 had participated the study.Results:Incidences of premature rupture of membrane and placental abruption in IVF-ET group were significant higher than in ICSI group(χ2=5.93,6.01;P0.05);Ratios of pregnancy-induced hypertension and intrahepatic cholestasis of pregnancy between IVF-ET and ICSI group were no significant differences(χ2=2.68,1.37;P0.05);Ratio of abortion in IVF-ET group was significant higher than that in ICSI group(χ2=5.09;P0.05).Conclusion:The risk of twin pregnancy by IVF-ET is higher than by ICSI,IVF-ET and ICSI maybe are not the main cause of pregnancy-induced hypertension and intrahepatic cholestasis of pregnancy.