ROLE OF AMINO ACIDS, INTRAVENOUS HYDRATION AND PROGESTOGENS IN OLIGOHYDRAMNIOS AND IUGR.

OBJECTIVES: To verify and evaluate the role of maternal intravenous infusion of fluids, amino acids and progestogens in increasing the liquor amount and fetal weight in IUGR and oligohydramnios. METHODS: 90 patients with USG confirmed oligohydramnios and IUGR were admitted and divided into three groups. Group I was given high protein diet, bed rest, Intravenous fluids Ringer lactate and 5% Dextrose in 2:1 ratio on alternate days. Group II received fluid therapy RL and 5% dextrose in the ratio of 2:1 on alternate days for three days, amino acid drip 100ml twice daily on alternate days for 3 days a week and Group III received fluid therapy and amino acid infusion on alternate days along with natural progestogens 100mg once a week. Liquor was assessed clinically as well as by USG after a week and after 3 weeks. RESULTS: Amniotic fluid index increased in Group II and Group III significantly and increase in fetal weight was more so in Group III. Normal deliveries without complications were much more in Group II and Group III. Fetal distress was reduced in Group II and comparatively more so in Group III. CONCLUSION: Intravenous infusion of amino acids along with Intravenous fluid therapy given on alternate days as a weekly regime with addition of progestogens to this regime was beneficial to both the mother and fetus in oligohydramnios and IUGR. INTRODUCTION: IUGR is failure of the fetus to reach genetic potential for growth1 . 24 - 30% incidence in developing country2. It is multifactorial, maternal, fetal and placental factors and environmental toxins interfere with normal growth mechanism 1 . (8). Fetus with IUGR has got increased risk of disease 3 and death during antenatal, intrapartum, neonatal, paediatric and adult life. Short term morbidities like prematurity, RDS, necrotising