IL-17C regulates the innate immune function of epithelial cells in an autocrine manner

Vladimir Ramirez-Carrozzi,Arivazhagan Sambandam,Elizabeth Luis,Zhongua Lin,Surinder Jeet,Justin Lesch,Jason A. Hackney,Janice Kim,Meijuan Zhou,Joyce Lai,Zora Modrusan,Tao Sai,Wyne P. Lee,Min Xu,Patrick Caplazi,Lauri Diehl,Jason de Voss,Mercedesz Balazs,Lino C. Gonzalez,Harinder Singh,Wenjun Ouyang,Rajita Pappu

IL-17C regulates the innate immune function of epithelial cells in an autocrine manner

2011

IL-17C is induced in epithelia by bacterial and inflammation stimuli. Pappu and colleagues show that IL-17C signals in an autocrine manner through the IL-17RA-IL-17RE receptor complex to regulate epithelial immune responses.

Keywords:

Autocrine signalling
IL 17 family
Immunology
Cell biology
Inflammation
Immune system
Biology
Proinflammatory cytokine
Innate immune system
Innate lymphoid cell
Receptor
receptor complex

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