Dilation of the Aorta Ascendens Forms Part of the Clinical Spectrum of HCN4 Mutations
2016
The HCN4-channel conducts the hyperpolarization-activated pacemaker current (“funny” current, If) in the sinoatrial node and mutations in the HCN4 gene are a long recognized genetic cause of sinus bradycardia [(1)][1]. Recently, the phenotypic spectrum of HCN4 mutations has been extended with
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