Design and implementation of pragmatic clinical trials using the electronic medical record and an adaptive design

Kelly Claire Simon,Samuel Tideman,Laura Hillman,Rebekah Lai,Raman Jathar,Yuan Ji,Stuart Bergman‐Bock,James Castle,Tiffani Franada,Thomas Freedom,Revital Marcus,Angela Mark,Steven Meyers,Susan Rubin,Irene Semenov,Chad Yucus,Anna Pham,Lisette Garduno,Monika Szela,Roberta Frigerio,Demetrius M. Maraganore

Design and implementation of pragmatic clinical trials using the electronic medical record and an adaptive design

2018

Objectives: To demonstrate the feasibility of pragmatic clinical trials comparing the effectiveness of treatments using the electronic medical record (EMR) and an adaptive assignment design.

Keywords:

Clinical trial
Biomedical engineering
Medical record
Medicine
Medical physics
Precision medicine
Documentation
Personalized medicine
Randomization
Workflow
Clinical decision support system
Proof of concept

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