Zinc complexation improves angiotensin II receptor type 1 blockade and in vivo antihypertensive activity of telmisartan.

Valeria R. Martínez,María Victoria Aguirre,Juan Santiago Todaro,Augusto Martins Lima,Nikolaos Stergiopulos,Evelina G. Ferrer,Patricia Am Williams

Zinc complexation improves angiotensin II receptor type 1 blockade and in vivo antihypertensive activity of telmisartan.

2020

Valeria R. Martínez
María Victoria Aguirre
Juan Santiago Todaro
Augusto Martins Lima
Nikolaos Stergiopulos
Evelina G. Ferrer
Patricia Am Williams

Background: Angiotensin II receptor blockers were designed as therapeutic agents to block the binding site of the angiotensin II receptor type 1 (AT1R). Methodology: The structure of telmisartan wa...

Keywords:

Pharmacology
Ligand (biochemistry)
Blockade
Binding site
Chemistry
Angiotensin II Receptor Blockers
Telmisartan
Angiotensin II receptor type 1
In vivo
Zinc

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