Computer-aided Response Surface Modeling Integrated with Parameter Optimization by a Genetic Algorithm for Biofuel Production.

A spacer (55) on a device for connecting two glass plates (31, 32) to form an edge-bonded insulating-glass pane by injecting a strand (67) of an initially pasty and subsequently solidifying material, adhering to the two glass plates (31, 32), over the entire periphery along the edge of the pane into the gap between the two glass plates held at a distance from one another is described. The spacer (55) has two rollers (70, 71) which are arranged next to one another with axes of rotation parallel to one another and to the pane running plane (10) and at right angles to the determined direction (III) of the relative movement between the nozzle (36) and the glass plates (31, 32) and of which one (70) is intended to rest against the inner surface of one glass plate (32) and the other (71) is intended to rest against the inner surface of the other glass plate (31).