An expedient solvent-free C-benzylation of 4-hydroxycoumarin with styrenes
2021
An efficient straightforward solvent-free C(3)-benzylation of 4-hydroxycoumarin with styrenes is performed by heating the reactants in the presence of p-toluenesulfonic acid. By this procedure, benzylated 4-hydroxycoumarin derivatives which exhibit various biological activities were obtained.
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