Limited risk compensation among women who inject drugs: Results from the Project SHE PrEP Demonstration Study in Philadelphia.

ABSTRACT The impact of pre-exposure prophylaxis (PrEP) uptake on sexual and injection-related behaviors among women who inject drugs (WWID) is poorly understood. Over 24-weeks, PrEP uptake among WWID was associated with increased sharing of injection equipment but not syringes and no changes in condomless sex, providing limited evidence of risk compensation in this vulnerable population.