A model for metabolic activation of dialkylnitrosamines. Oxidative dealkylation of N-nitroso-2-(alkylamino)acetonitrile by flavin mimic in aqueous solution

Abstract Oxidation-active flavin mimic, benzo[1,2-g, 5,4-g′]dipteridine (BDP), is found to react with N-nitroso-2-(alkylamino)acetonitrile via oxidative dealkylation in aqueous solution. From the kinetic investigations, the oxidation mechanism is proposed.