Identification of genomic mutations associated with clinical outcomes of induction chemotherapy in patients with head and neck squamous cell carcinoma

Chan-Young Ock,Bongjun Son,Bhumsuk Keam,Seung-Youn Lee,Jaewoo Moon,Hwanjong Kwak,Sehui Kim,Tae Min Kim,Yoon-Kyung Jeon,Seong Keun Kwon,J-Hun Hah,Se-Hoon Lee,Tack-Kyun Kwon,Dong-Wan Kim,Hong-Gyun Wu,Myung-Whun Sung,Dae Seog Heo

Identification of genomic mutations associated with clinical outcomes of induction chemotherapy in patients with head and neck squamous cell carcinoma

2016

Chan-Young Ock
Bongjun Son
Bhumsuk Keam
Seung-Youn Lee
Jaewoo Moon
Hwanjong Kwak
Sehui Kim
Tae Min Kim
Yoon-Kyung Jeon
Seong Keun Kwon
J-Hun Hah
Se-Hoon Lee
Tack-Kyun Kwon
Dong-Wan Kim
Hong-Gyun Wu
Myung-Whun Sung
Dae Seog Heo

Purpose We performed deep sequencing of target genes in head and neck squamous cell carcinoma (HNSCC) tumors to identify somatic mutations that are associated with induction chemotherapy (IC) response.

Keywords:

Pathology
Head and neck cancer
Head and neck squamous-cell carcinoma
Deep sequencing
Induction chemotherapy
Somatic cell
Biology
Internal medicine
Oncology
Gene
in patient
Hematology

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