헤어미용사의 직업성 접촉피부염에 대한 5가지 천연물의 효과

Hairdressing is one of the most hazardous occupations for the skin. Contact dermatitis of the hands is a well recognized and frequently observed condition in the hairdressing industry. The aim of this study was antioxidative and antimicrobial activity of 5 natural substances (Phaseolus radiatus: P. radiatus, Capsosiphon fulvescen: C. fulvescen, Salicornia europea: S. europea, Caesalpinia sappan: C. sappan, Chamaecyparis obtusa: C. obtusa) and relieve effect of it`s mixture consisted spray. DPPH and SO scavenging were measured, and Staphylococus aureus (S. aureus) and Staphylococus epidermidis (S. epidermidis) inhibition were observed. Mixture of 5 natural materials were prepared and was applicate on dermatitis hand of 7 hairdressers in 4 weeks. In the result, DPPH and SO scavenging of the materials in 0.45~1.30 mg/ml and 0.21~1.6.0 mg/ml concentration was shown similar to positive control 0.1 mg/ml BHT and Vit C 0.1 mg/ml. C. obtusa ethanol extract in 50 mg/ml has higher antimicrobial activity by formation smaller size clear zone than positive control GM against S. aureus and S. epidermidis strain; 18 mm clear zone was found in C. sappan ethanol extract in 5 mg/ml that is larger than those made in GM 20 μl/ml. After using spray for 4 weeks, the common symptoms on hand such as dryness, irritation, feel of burning, and itchiness were almost disappeared and relieved. In conclusion, spray from P. radiatus, C. fulvescen, S. europea, C. sappan, C. obtusa extract is highly effective that can be used as the cosmeceuticals to relieve occupational contact dermatitis in hair dressers.