Anti-microbial Studies of Potential Cyclopentanone derived Spiropyrroidines

A Series of Various cyclopentanone derived spiro-pyrrolidines were synthesized using 1, 3-dipolar cycloaddition methodology. The compounds found to have very good antimicrobial properties and some of the compounds shown properties greater than the reference compounds. The attachment of cyclopentanone moiety to spiropyrrolidines enhanced the antimicrobial properties and it is shown in the results.