PS1 - 2. Role of the tumour suppressor CDKN2A/p16INK4a in the development of perivascular adipose tissue

Kristiaan Wouters,Sarah Anissa Hannou,Céline Cudejko,Jonathan Vanhoutte,Anthony Lucas,Kadiombo Bantubungi,Emanuelle Vallez,Emanuel Bouchaert,Casper G. Schalkwijk,Anne Tailleux,Bart Staels,Réjane Paumelle

PS1 - 2. Role of the tumour suppressor CDKN2A/p16INK4a in the development of perivascular adipose tissue

2013

Kristiaan Wouters
Sarah Anissa Hannou
Céline Cudejko
Jonathan Vanhoutte
Anthony Lucas
Kadiombo Bantubungi
Emanuelle Vallez
Emanuel Bouchaert
Casper G. Schalkwijk
Anne Tailleux
Bart Staels
Réjane Paumelle

Genome wide association studies have been linked the CDKN2A/B locus to an increased risk for atherosclerosis, type 2 diabetes and aneurysm development. These conditions all are linked to perivascular adipose tissue (pAT) accumulation, which has an inflammatory phenotype.

Keywords:

Locus (genetics)
Cancer research
Genome-wide association study
Adipose tissue
Immunology
CDKN2A
Type 2 diabetes
Phenotype
Rosiglitazone
Diabetes mellitus
Biology
Pathology
Suppressor
increased risk

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