Corticosteroid therapy in collagen disease

: Corticosteroids are used commonly in the management of collagen disease and related condition. The degree of disease activity and clonicity should be clearly evaluated as therapeutic strategies of corticosteroids. High dose corticosteroids including pulse-therapy is useful for SLE with CNS-lupus, lupus nephritis and hemolytic anemia. Dermatomyositis also require high dose corticosteroids and it should keep for long time. PN is effective combination therapy of corticosteroids and cyclophosphamide. PMR and Temporal Arthritis well response dramatically to corticosteroids. RA should not be administrate over 7.5 m/day of CS. Intra-auticular therapy and alternate-day therapy are recommended in in-active RA.