Efficient up-conversion in Yb:Er:NaT(XO4)2 thermal nanoprobes. Imaging of their distribution in a perfused mouse.

The authors thankfully acknowledge the financial support by Ministry of Economy and Competitiveness and the European Regional Development Fund grant number MAT2014-56607-R, the Spanish Ministry of Economy and Competitiveness support as a Severo Ochoa Center of Excellence, grant nunber SEV-2015-0505, and by the Pro CNIC Foundation. The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript.; This work has been supported by the Ministry of Economy and Competitiveness (MINECO) and by the European Regional Development Fund through MAT2014-56607-R project. The CNIC is supported by the Ministry of Economy, Industry and Competitiveness (MEIC) and the Pro CNIC Foundation, and is a Severo Ochoa Center of Excellence (SEV-2015-0505). Optical microscopy was carried out at the Molecular and Functional Imaging Unit, ICTS ReDIB TRIMA@CNIC. The authors are in debt with the histology facility of CNB-CSIC for tissue section preparation and with A. M. Santos Beneit (CNIC) for his help in image analysis.