[Changes of left ventricular remodeling in hypertension patients with carotid atherosclerosis of phlegm-dampness syndrome].

Objective To study changes of left ventricular remodeling(LVR)in hypertension patients with carotid atherosclerosis(CAS)of phlegm-dampness syndrome(PDS).Methods Color Doppler ultrasonography data of CAS were observed in223 hypertension patients with CAS(as the hypertension group,including119 patients of the PDS group and 104 of the non-PDS group),81 CAS patients with non-hypertension,and 19 non-hypertension non-CAS patients(as the control group).The difference in the degree of LVR was compared among the above groups.Results The left ventricular posterior wall thickness(LVPWT),inter ventricular septum thickness(IVS),E/A were higher in the hypertension group than in the non-hypertension group(P0.05).The left ventricular end-diastolic dimension(LVEDD),left ventricular end-systolic diameter(LVESD),stroke volume(SV)were higher in the soft plaque hypertension group and the soft plaque non-hypertension group than in the hard plaque group,the thickening intimal group,and the normal intimal group(P0.01,P0.05).The LVEDD,LVESD,and SV were higher,and the ejection fraction(EF)was lower in the PDS hypertension group than in the non-PDS hypertensiongroup(all P0.05).Of them,LVEDD,LVESD,and SV were higher in the soft plaque group than in the hard plaque group(P0.01),the thickening intimal group(P0.01)and the normal intimal group(P0.05).There was no statistical difference in PDS hypertension between the soft plaque group and the hard plaque group(P0.05).Conclusion The hypertension patients with CAS of PDS might be correlated to LVR,and LVR was more obviously in the soft plaque patients.