Clinical and sociodemographic characteristics associated with suicidal ideation in depressed outpatients

Objective: To identify clinical and sociodemographic characteristics associated with suicidal ideation (SI) among patients seeking care for depression in routine primary and psychiatric care settings.Methods: We examined data from 4041 treatment-seeking outpatients with major depressive disorder (MDD) to compare baseline sociodemographic and clinical characteristics of those with and without SI, and the presence or absence of baseline depressive symptoms and psychiatric comorbidities in those with SI.Results: SI was significantly (P Conclusions: Consistent with past findings, increased rates of SI were associated with greater depressive symptom severity as well as other features suggestive of severity of illness. Our results confirm previous findings of associations between SI and panic and (or) phobic symptoms and anxiety, but did not confirm previous findings of an association between SI and alcohol or drug use and (or) dependence. While selective serotonin reuptake inhibitor monotherapy appeared significantly helpful in reducing SI during the course of treatment, the presence of SI at baseline was found to be a associated with decreased treatment response, with patients reporting SI at the start of treatment being less likely to achieve remission.Clinical Trial Registration Number: Sequenced Treatment Alternatives to Relieve Depression, NCT00021528.Caracteristiques cliniques et sociodemographiques associees a l'ideation suicidaire chez les patients externes deprimesObjectif : Identifier les caracteristiques cliniques et sociodemographiques associees a l'ideation suicidaire (IS) chez les patients requerant des soins pour la depression dans des contextes reguliers de soins de premiere ligne et psychiatriques.Methodes : Nous avons examine les donnees de 4041 patients externes souffrant de trouble depressif majeur (TDM) demandant un traitement afin de comparer les caracteristiques cliniques et sociodemographiques de depart des patients avec et sans IS, et la presence ou l'absence de symptomes depressifs de depart et de comorbidites psychiatriques chez les patients avec IS.Resultats : L'IS etait significativement (P Conclusions : Conformement aux resultats precedents, les taux accrus d'IS etaient associes a la gravite accrue des symptomes depressifs ainsi qu'a d'autres caracteristiques indiquant la gravite de la maladie. Nos resultats confirment les resultats precedents d'associations entre NS et les symptomes paniques et (ou) phobiques et l'anxiete, mais ne confirment pas les resultats precedents d'une association entre NS et l'utilisation d'alcool ou de drogue et (ou) la dependance a ceux-ci. Bien que la monotherapie par inhibiteur specifique du recaptage de la serotonine semble significativement utile pour reduire NS durant le cours du traitement, la presence d'IS au depart a ete observee etre associee a une reponse reduite au traitement, et les patients qui declaraient une IS au debut du traitement etaient moins susceptibles d'obtenir une remission. …